Low hematocrit impairs gastric mucosal CO2 removal during experimental severe normovolemic hemodilution

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Low hematocrit impairs gastric mucosal CO2 removal during experimental severe normovolemic hemodilution.

OBJECTIVE The net effects of acute normovolemic hemodilution with different hemoglobin levels on splanchnic perfusion have not been elucidated. The hypothesis that during moderate and severe normovolemic hemodilution, systemic and splanchnic hemodynamic parameters, oxygen-derived variables, and biochemical markers of anaerobic metabolism do not reflect the adequacy of gastric mucosa, was tested...

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Hemodynamic compensation during acute normovolemic hemodilution.

To the Editor:—Acute normovolemic hemodilution (ANH) causes a reduction in arterial oxygen content because of reduced hemoglobin concentration. The primary compensatory mechanism during ANH is an increase in cardiac output to maintain systemic oxygen delivery. Therefore, the lower limit of an acceptable hemoglobin concentration is related to how low hemoglobin can be reduced without jeopardizin...

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Hemodynamic Compensation during Acute Normovolemic Hemodilution

To the Editor:—Acute normovolemic hemodilution (ANH) causes a reduction in arterial oxygen content because of reduced hemoglobin concentration. The primary compensatory mechanism during ANH is an increase in cardiac output to maintain systemic oxygen delivery. Therefore, the lower limit of an acceptable hemoglobin concentration is related to how low hemoglobin can be reduced without jeopardizin...

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Transesophageal echocardiographic hemodynamic monitoring during preoperative acute normovolemic hemodilution.

BACKGROUND Preoperative acute normovolemic hemodilution may compromise oxygen transport. The aims of our study were to describe the hemodynamic effects of normovolemic hemodilution and to determine its effect on systolic and diastolic cardiac function by multiplane transesophageal echocardiography. METHODS In eight anesthetized patients (aged 13-51 yr) without heart disease, hemoglobin was re...

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Acute decrease in renal microvascular PO2 during acute normovolemic hemodilution.

Large differences in the tolerance of organ systems to conditions of decreased O(2) delivery such as hemodilution exist. The kidney receives approximately 25% of the cardiac output and O(2) delivery is in excess of the oxygen demand under normal circumstances. In a rat model of acute normovolemic hemodilution (ANH), we studied the effect of reduced hematocrit on renal regional and microvascular...

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ژورنال

عنوان ژورنال: Clinics

سال: 2006

ISSN: 1807-5932

DOI: 10.1590/s1807-59322006000500012